Table 1.
Demographical and clinical baseline characteristics of patients by group in the study (randomized patients).
| Baseline characteristics | Decolonization group (n=31), % | Observation group (n=31), % |
|---|---|---|
|
| ||
| Age (years, median, interquartile range) | 49 (39–63) | 49 (35–63) |
|
| ||
| Sex (female) | 15 (48.4) | 16 (51.6) |
|
| ||
| BMI (kg/m2, median, interquartile range) | 25.5 (24.1–28.4) | 25.8 (24.2–27.6) |
|
| ||
| Primary disease: | ||
| Acute myeloid leukemia | 17 (54.8) | 16 (51.6) |
| Multiple myeloma | 7 (22.6) | 9 (29.0) |
| Hodgkin’s lymphoma | 1 (3.2) | - |
| Chronic lymphocytic leukemia | 3 (9.7) | 4 (12.9) |
| Myelodysplastic syndrome | 1 (3.2) | 1 (3.2) |
| Acute lymphocytic leukemia | 2 (6.5) | 1 (3.2) |
|
| ||
| Primary disease stage: | ||
| Progression | 19 (61.3) | 17 (54.8) |
| Remission | 12 (38.7) | 14 (45.2) |
|
| ||
| Level of neutropenia on day 1 of trial: | ||
| <100 cells/mm3 | 15 (48.4) | 18 (58.1) |
| 100–500 cells/mm3 | 5 (16.2) | 3 (9.7) |
| >500 cells/mm3 | 11 (35.5) | 10 (32.3) |
|
| ||
| MDR/XDR resistant species at baseline rectal swab: | ||
| K. pneumoniae | 16 (51.6) | 13 (41.9) |
| E. coli | 4 (13.0) | 8 (25.8) |
| A. baumannii | 5 (16.1) | 5 (16.1) |
| P. aeruginosa | 6 (19.4) | 5 (16.1) |
|
| ||
| Carbapenem resistant species at baseline rectal swab: | ||
| K. pneumoniae | 8(25.8) | 7(22.6) |
| E. coli | 2(6.5) | 1(3.2) |
| A. baumannii | 5(16.1) | 4(12.9) |
| P. aeruginosa | 3(9.7) | 4(12.9) |
|
| ||
| Infections caused by colonizing microorganism in previous 6 months: | 4 (12.9) | 3 (9.7) |