Table 1.
Clinical characteristics of the study subjects
| TDI-OA (n = 68) | AEC (n = 100) | NC (n = 122) | Pvalue | |||
|---|---|---|---|---|---|---|
| TDI-OA vs. AEC | TDI-OA vs. NC | AEC vs. NC | ||||
| Age (years)a | 42 ± 10.4 | 41.17 ± 8.7 | 43.14 ± 12.2 | 0.579 | 0.519 | 0.164 |
| Sex (male, %)b | 46 (67.6%) | 68 (68.0%) | 55 (45.1%) | 0.997 | 0.004 | 0.001 |
| Atopy (%)b | 25 (46.3%) | NA | 56 (57.9%) | NA | 0.001 | 0.634 |
| Smoking history (%)b | 15 (27.3%) | 40 (48.8%) | 18 (15.3%) | 0.034 | 0.170 | <0.001 |
| TDI exposure duration (years)a | 6.19 ± 3.97 | 12.2 ± 8.21 | NA | 0.005 | NA | NA |
| Asthma duration (years)a | 6.68 ± 4.11 | NA | NA | NA | NA | NA |
| Serum total IgE (IU/L)a | 263.17 ± 556.77 | 241.17 ± 656.82 | 46.08 ± 33.77 | 0.367 | 0.211 | 0.520 |
| FEV1 (% predicted)a | 86.4 ± 23.5 | 90.2 ± 21.2 | NA | 0.642 | NA | NA |
| Mch PC20 (mg/mL)a | 8.04 ± 14.64 | NA | NA | NA | NA | NA |
TDI-OA TDI-induced occupational asthma, AEC asymptomatic exposed, NC healthy normal control, FEV1 forced expiratory volume in 1 s, Mch PC20 concentration of methacholine required to produce a 20% decrease in FEV1, NA not available
a Data are shown as the mean ± SD, P value obtained with Student’s t test
b Data are shown as the prevalence (%), P value obtained with the χ2 test