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. 2018 Apr 20;50(4):38. doi: 10.1038/s12276-018-0053-x

Fig. 2. LJ -2698 improved kidney morphology in db/db mice.

Fig. 2

LJ-2698 was administered to db/db mice at doses of 1.5, 5, or 10 mg/kg. CMC was administered to control db/db and db/m mice. After 12 weeks of treatment, mice were sacrificed, and the right kidney was fixed and sectioned. (a) Sections were stained with PAS reagent. The scale bar indicates 10 μm; the original magnification was ×630. (b) Glomerular volume and (c) FMA were then analyzed using Image-Pro Plus 4.5.1. Data are presented as the mean ± SE of 7–10 mice/group. *p < 0.05 vs. db/m and p < 0.05 vs. db/db mice