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. 2018 Apr 27;50(4):51. doi: 10.1038/s12276-018-0077-2

Fig. 1. Main epigenetic targets.

Fig. 1

Current inhibitors act on three different epigenetic levels: DNA methylation, histone methylation or acetylation, and chromatin reading. This scheme highlights the most promising drugs that target proteins involved in these processes with a subset already under clinical trials or even approved for treatment of certain malignancies