Table 2.
Current epigenetic drugs clinical trials in Neuroblastoma
| Name of the drug | Type of drug | Phase | Estate | Number |
|---|---|---|---|---|
| Decitabine | DNMT pan-inhibitor | Phase I | Complete | NCT01241162 |
| Phase I | Complete | NCT00075634 | ||
| Genistein | DNMT pan-inhibitor | Phase II | Recruiting | NCT02624388 |
| Vorinostat | HDACi class I and II inhibitor |
Phase I | Complete | NCT00217412 |
| Phase I | Complete | NCT01132911 | ||
| Phase II | Ongoing but not recruiting | NCT02035137 | ||
| Phase I | Recruiting | NCT02559778 | ||
| Phase I | Complete | NCT01019850 | ||
| Phase I | Complete | NCT01208454 | ||
| VAP | HDACi class I and II inhibitor |
Phase I | Ccomplete | NCT01204450 |
| 4-PB | HDACi pan-inhibitor |
Phase I | Complete | NCT00001565 |
| GSK525762 | iBET | Phase I | Recruiting | NCT01587703 |