Skip to main content
. 2018 Apr 27;50(4):49. doi: 10.1038/s12276-018-0075-4

Fig. 3. Protectin DX enhanced sodium channel and Na, K-ATPase expression and Na, K-ATPase activity in LPS-induced acute lung injury in vivo.

Fig. 3

Protectin DX (5 µg/kg) was injected into the caudal veins of Sprague-Dawley rats 8 h after LPS (14 mg/kg) stimulation; the rats were ventilated for 60 min, and the right lung tissues were harvested to measure the protein expression levels of the sodium channel α, β, and γ subunits (a, b, c) and Na, K-ATPase α1 and β1 subunits (d, e) by western blotting. In addition, the Na, K-ATPase activity in the lung tissue homogenates was detected by kits (f). The data are presented as the mean ± SD. n = 8. PDX protectin DX. Alcohol was the solvent for protectin DX. *p < 0.05, **p < 0.01 versus the control group; †p < 0.05, ††p < 0.01 versus the LPS group; ‡p < 0.05, ‡‡p < 0.01 versus the LPS + alcohol group