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. 2018 Apr 13;50(4):22. doi: 10.1038/s12276-018-0041-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, and provide a link to the Creative Commons license. You do not have permission under this license to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 1 — a Rotarod test (left panel) and mNSS (right panel) test in MCAo rats with various treatment paradigms of IV-hUMSCs (n = 10 in each group). D0 represents the day of MCAo induction in rats. The data were analyzed using the mixed ANOVA test. *p < 0.05 between G1 group and G4 group. b Infarct size using Cresyl violet staining at 8 weeks post MCAo in rats treated with IV-hUMSCs at various cell doses and delivery time points (n = 7 for each group). c Rotarod test (left panel) and mNSS (right panel) test of an independent study of IV-hUMSCs at 1 × 10⁶ cells at 24 h post MCAo (n = 10 in each group). The data were analyzed using the mixed ANOVA test. d Measurement of infarct size using 2, 3, 5-triphenyltetrazolium chloride (TTC) staining at 72 h post MCAo in an independent study of IV-hUMSCs at 1 × 10⁶ cells at 24 h after MCAo (n = 5 in each group). All data are presented as the mean ± SEM. *p < 0.05