Skip to main content
. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Alzheimers Dement. 2018 Jan 9;14(5):664–679. doi: 10.1016/j.jalz.2017.11.010

Fig. 3. DNA damage, CCE and OL degeneration are highly correlated in the frontal cortex.

Fig. 3

The histological data of OL degeneration, OL-specific DNA damage, CCE and ATM activation were examined for correlations using Pearson test. A–C DSB-DNA damage, OL degeneration and CCE were strongly correlated; D, E The CCE of mOL was significantly associated with their decline in number, but not their apoptosis. F–H A robust correlation between ATM activation, DSB-DNA damage and OL losses were observed. All Pearson test. Data categorized by clinical phenotype (dark square = NC, open square = DEM, red square = AD)