Table 2.

Cardio-metabolic risk factor burden over time by cardiovascular autonomic neuropathy status in adolescents and young adults with type 1 and type 2 diabetes.

	Type 1 diabetes = 1646			Type 2 diabetes = 252
Variable	No CAN	CAN	P-value	No CAN	CAN	P-value
AUC BMI-z	20.6 ± 0.9	20.6 ± 0.9	0.75	21.9 ± 0.7	22 ± 0.6	0.50
AUC DBP	65.9 ± 7.2	68 ± 7.6	<0.001	73.1 ± 6.7	75.6 ± 9.7	0.18
AUC SBP	103.5 ± 9	107.5 ± 9	<0.001	116.6 ± 9.3	119.7 ± 11.8	0.22
AUC HbA1c	8.5 ± 1.3	8.8 ± 1.5	0.005	8.4 ± 2.4	8.6 ± 2.3	0.65
AUC LDL-cholesterol	93.5 ± 22.3	95.1 ± 24.2	0.53	104.1 ± 30.7	99.6 ± 26.6	0.54
AUC Triglycerides	79.2 ± 43.8	92 ± 59.6	0.001	149.6 ± 121.7	225.3 ± 221.8	0.005
AUC HDL-cholesterol	56.1 ± 11.8	54.7 ± 10.6	0.10	42.4 ± 10.9	40.1 ± 10.4	0.13

All data are presented as mean ± SD. CAN: cardiovascular autonomic neuropathy, BMI: body mass index, SPB and DBP: systolic and diastolic blood pressure, HDL: high density lipoprotein, LDL: low density lipoprotein, AUC: area under the curve derived from data collected at baseline, 1,2, 5 year follow-up and the current cohort visits