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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Bioorg Med Chem Lett. 2018 Mar 9;28(10):1972–1980. doi: 10.1016/j.bmcl.2018.03.020

Table 7.

In Vivo Exposure of Compound 18b Following IP Administration to Micea

Time Post-Dose 30 min 2 h 4 h 7 h
Plasma Conc. (ng/mL) 110 138 10 BLQ
Brain Conc. (ng/g) 54 BLQ BLQ BLQ
a

CD-1 mice were injected intraperitoneally with a single 10 mg/kg dose. The data shown are mean values from 2 mice at each time point. BLQ = Below Limit of Quantification.