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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Matrix Biol. 2017 Nov 7;75-76:260–270. doi: 10.1016/j.matbio.2017.10.005

Fig. 1.

Fig. 1

Schematic representation of decorin-evoked endothelial cell autophagy. (A) Mechanistic depiction of decorin-evoked endothelial cell autophagy downstream of VEGFR2. (B) Differential interference contrast (DIC) images of HUVEC treated for 6 hours of decorin (200 nM) upon silencing of TFEB, utilizing a specific siRNA, and probed for Beclin 1 (green) and LC3 (red). Arrows, in the top right panel, indicate the dually positive Beclin 1/LC3 autophagosomes as evoked by decorin in scramble transfected cells. Nuclei have been stained with DAPI (blue). All images were taken with the same exposure, gain, and intensity. Scale bar ~ 10 μm.