Table.
Adjusted hazard ratios (95% confidence interval) for haemorrhagic and occlusive stroke according to birth weight in Swedish men and women born between 1915 and 1929*
| Haemorrhagic stroke
|
Occlusive stroke
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No | Adjusted for core variables†‡ | Adjusted for core variables and head circumference | Adjusted for core variables and birth length | Adjusted for core variables, head circumference, and birth length | No | Adjusted for core variables† | Adjusted for core variables and head circumference | Adjusted for core variables and birth length | Adjusted for core variables, head circumference, and birth length | ||
| Birth weight (g): | |||||||||||
| <2750 | 17 | 1 | 1 | 1 | 1 | 53 | 1 | 1 | 1 | 1 | |
| 2750-3249 | 33 | 0.49 (0.27 to 0.89) |
0.41 (0.22 to 0.77) |
0.46 (0.24 to 0.87) |
0.39 (0.20 to 0.77) |
181 | 0.90 (0.66 to 1.22) |
0.91 (0.67 to 1.25) |
0.90 (0.65 to 1.25) |
0.92 (0.66 to 1.28) |
|
| 3250-3749 | 62 | 0.54 (0.32 to 0.94) |
0.41 (0.22 to 0.78) |
0.48 (0.24 to 0.95) |
0.38 (0.18 to 0.80) |
274 | 0.80 (0.59 to 1.07) |
0.82 (0.59 to 1.14) |
0.80 (0.56 to 1.13) |
0.82 (0.57 to 1.18) |
|
| 3750-4249 | 28 | 0.46 (0.25 to 0.84) |
0.35 (0.17 to 0.73) |
0.41 (0.19 to 0.91) |
0.33 (0.14 to 0.78) |
159 | 0.87 (0.64 to 1.19) |
0.90 (0.63 to 1.29) |
0.85 (0.58 to 1.26) |
0.88 (0.58 to 1.33) |
|
| ⩾4250 | 3 | 0.17 (0.05 to 0.59) |
0.14 (0.04 to 0.52) |
0.18 (0.05 to 0.73) |
0.15 (0.04 to 0.64) |
40 | 0.79 (0.52 to 1.20) |
0.82 (0.52 to 1.31) |
0.78 (0.48 to 1.28) |
0.81 (0.48 to 1.37) |
|
| Hazard ratio per 1 kg increase in birth weight | 0.59 (0.43 to 0.83) |
0.49 (0.32 to 0.75) |
0.53 (0.33 to 0.84) |
0.45 (0.27 to 0.76) |
0.93 (0.80 to 1.09) |
0.96 (0.80 to 1.16) |
0.94 (0.76 to 1.15) |
0.96 (0.76 to 1.20) |
|||
| Test for trend | P=0.009 | P=0.008 | P=0.05 | P=0.03 | P=0.29 | P=0.53 | P=0.38 | P=0.52 | |||
*
Analyses restricted to n=10 009 subjects with information available for all the variables in each stage of modelling.
†
Core variables=sex, period of birth, and social trajectory.
‡
Social trajectory consists of parental social characteristics (mother's civil status and social group) and indicators of participant's own social status in adulthood (social group, car ownership from 1960 census, education, income, and car ownership from 1970 census).