Table 2.
Comparison of Demographic Profile and Laboratory Parameters of Patients With and Without Post-TACE Liver Failure.
| Parameter | Post TACE liver failure |
P value | |
|---|---|---|---|
| Present (n = 17) | Absent (n = 42) | ||
| Age (years), mean ± sd | 49.1 ± 11.4 | 54.5 ± 13.3 | 0.142 |
| Sex (M:F) | 15:2 | 35:7 | 1.0 |
| Etiology | 0.322 | ||
| HBV | 7 (41.2%) | 24 (57.1%) | |
| HCV | 7 (41.2%) | 7 (16.7%) | |
| NASH | 1 (5.9%) | 3 (7.1%) | |
| Alcohol | 2 (11.8%) | 2 (4.8%) | |
| HBV and alcohol | 0 | 4 (9.5%) | |
| HBV and HCV co-infection | 0 | 1 (2.4%) | |
| Cryptogenic | 0 | 1 (2.4%) | |
| Clinical presentation | |||
| Abdominal pain | 9 (52.9%) | 21 (50.0%) | 1.0 |
| Weight loss | 6 (35.3%) | 20 (47.6%) | 0.563 |
| Fever | 6 (35.3%) | 5 (11.9%) | 0.062 |
| Bilirubin (mg/dl) | 1.4 (1.0–2.5) | 0.9 (0.6–1.3) | 0.006 |
| AST (IU/L) | 62 (49–122) | 55 (35.5–89) | 0.388 |
| ALT (IU/L) | 33 (21–81) | 43.5 (24.7–62) | 0.586 |
| Albumin (g/dl) | 3.6 (3.1–3.7) | 3.7 (3.3–4.3) | 0.109 |
| Alkaline phosphatase (IU/L) | 461 (300–482) | 290 (207–416) | 0.040 |
| Sodium (mEq/L) | 137 (135–140.5) | 137.5 (134–140) | 0.980 |
| Potassium (mEq/L) | 4.4 (3.2–4.8) | 4.0 (3.6–4.5) | 0.574 |
| Hemoglobin (g/dl) | 10.8 (9.1–12.2) | 11.6 (10.6–12.6) | 0.238 |
| Total leukocyte count (per mm3) | 4300 (2400–7200) | 5700 (4350–7425) | 0.186 |
| Platelet count (×103 per mm3) | 97 (50–160) | 130 (76.7–171.2) | 0.389 |
| Creatinine (mg/dl) | 0.9 (0.7–1.1) | 0.8 (0.7–1.0) | 0.794 |
| Alpha-fetoprotein (ng/ml) | 164 (8.1–2290) | 78.5 (8.1–714.7) | 0.586 |
| INR | 1.4 (1.3–1.5) | 1.3 (1.2–1.4) | 0.004 |
| CTP score | 7 (7–7.5) | 6 (5–7) | <0.001 |
| MELD | 10.5 (7.4–13.8) | 6.3 (4.9–10.4) | 0.005 |
| MELD-Na | 13.7 (12.1–16.5) | 12.5 (8.8–15.0) | 0.141 |
| ICG-PDR (%/min) | 7.4 (4.8–10.7) | 10.6 (7.5–15.3) | 0.008 |
| ICG-R15 (%) | 33.0 (20.3–48.7) | 21.4 (10.3–32.6) | 0.008 |
Abbreviations: HBV, Hepatitis B Virus; HCV, Hepatitis C Virus; NASH, non-alcoholic steatohepatitis; AST, aspartate aminotransferase; ALT, alanine transaminase; INR, international normalized ratio; CTP, Child-Turcotte-Pugh; MELD, model for end stage liver disease; MELD-Na, model for end stage liver disease-sodium; ICG-PDR, indocyanine green-plasma disappearance rate.