FIGURE 4.

BTP2 inhibits SOCE. (A) Representative traces of SOCE in response to subsequent application of 2.5 mM extracellular Ca²⁺ (white box at bottom) after pre-incubation with 10 μM TG (black box at the top) with (red line), or without (black line) 1 μM BTP2. (B) Summary bar graph shows [Ca²⁺]_i increase by addition of extracellular Ca²⁺ without (open column) or with 1 μM BTP2 (gray column). Each column indicates the mean ± SE of 9–10 independent experiments. Statistically significant differences between columns (shown by solid lines) are denoted by asterisks, ^∗P < 0.05.