Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model parameter estimates and their coefficients of variation (% CV) for the characterization of the concentration–response curves.
| Drug | R0 (%) (CV %) | IC50 (nM) (CV %) | γ (CV %) | Imax (CV %) |
|---|---|---|---|---|
| Dasatinib | 91.8 (9) | 58 (50) | 0.42 (21) | 0.99 (4) |
| Everolimus | 100 (fixed) | 3.96 (58) | 1 (48) | 0.37 (0.64) |
| Paclitaxel | 100 (fixed) | 151 (30) | 1 (35) | 0.83 (10) |
R0, baseline % cells viability; Imax, maximum effect; IC50, inhibitory concentration for 50% of Imax; γ, Hill coefficient.
