Table 1.
Baseline parameters during 24 h treatment period.
| NTFe (self-ventilating, 24 h iv fentanyl at normothermia, n = 6) | NTCTR (self-ventilating, controls at normothermia, n = 7) | |
|---|---|---|
| Median weight [kg, (IQR)] | 1.75 (1.63–1.86) | 1.36 (1.29–1.42) |
| Sex | 2 females, 4 males | 4 females, 3 males |
| Median age [h, (IQR)] | 10 (9–12) | 10 (9.5–11) |
| Median heart rate [/min, (IQR)] | 159 (153–164) | n/a |
| Median arterial blood pressure [mmHg, (IQR)] | 53 (46.8–55) | n/a |
| Median tcSO2 [%, (IQR)] | 98 (97–99) | n/a |
| Median pH (IQR) | 7.41 (7.38–7.45) | 7.46 (7.42–7.50) |
| Median glucose [mmol/l, (IQR)] | 5.9 (5.4–6.1) | 3.9 (3.4–4.3) |
| Median lactate [mmol/l, (IQR)] | 2.1 (1.4–3.1) | 3.3 (2.9–3.5) |
| Median fentanyl dosage [μg/kg/h, (IQR)] | 17.5 (15–20) | 0 |
Median (interquartile range) baseline parameters (weight, sex, and age), heart rate, arterial blood pressure, transcutaneous oxygen saturation (tcSO2), pH, blood glucose, and lactate levels of all 13 animals in the two treatment groups and median fentanyl dosage for 6 pigs receiving iv fentanyl.
IQR, interquartile range.
n/a: Data were not applicable; these animals were not cardiovascularly monitored as they were non-instrumented control animals (NTCTR).