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. 2018 May 1;12:25. doi: 10.3389/fncom.2018.00025

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Copyright © 2018 Hao, Yang and Lei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Four stimulus protocols. Stimulus protocol 1: synapse 1 in the P1 pathway receives a stimulus of 100 Hz for 1 s. Stimulus protocol 2: all synapses in the P1 pathway receive a stimulus of 100 Hz for 1 s. Stimulus protocol 3: all synapses in the P2 pathway receive a weak stimulus (5 Hz for 4 s). Stimulus protocol 4: all synapses in the P1 pathway receive a strong stimulus (100 Hz for 4 s) and all synapses in the P2 pathway receive a weak stimulus (5 Hz for 4 s) simultaneously.