Skip to main content
. 2018 May 1;8:127. doi: 10.3389/fcimb.2018.00127

Table 1.

Virus titers of the first (F1) to the fourth passages (F4) of the WT and NS1 mutant viruses in A549 cells.

Mean titers (log10 PFU/mL) ±SD F1 → (MOI = 0.001) F2 F3 F4
WT 5.6 ± 0.1 5.8 ± 0.2 5.5 ± 0.2 5.3 ± 0.1
R38A 4.1 ± 0.1 3.7 ± 0.1 3.4 ± 0.1 3.3 ± 0.2
K41A 4.5 ± 0.2 4.3 ± 0.1 4.2 ± 0.2 4.0 ± 0.1
R38A/K41A 3.3 ± 0.1 2.2 ± 0.1 NDa ND
a

ND means not detected.