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. 2018 May 1;9:484. doi: 10.3389/fphys.2018.00484

Table 4.

Dependencies of loop-derived parameters in COPD patients.

Ains cmH2O⋅L⋅s-1
Aexp cmH2O⋅L⋅s-1
ΔPalv cmH2O
RS P RS P RS P
Rins, cmH2O.L-1.s 0.414 <0.001 0.493 <0.001 0.578 <0.001
Rexp, cmH2O.L-1.s 0.405 <0.001 0.627 <0.001 0.617 <0.001
FEV1, L -0.177 0.044 -0.341 <0.001 -0.347 <0.001
FVC, L -0.230 0.008 -0.360 <0.001 -0.427 <0.001
FEV1/FVC, % -0.057 0.518 -0.143 0.105 -0.084 0.343
IC, L -0.084 0.339 -0.194 0.027 -0.244 0.005
VC, L -0.205 0.019 -0.279 0.001 -0.403 <0.001
TLC, L -0.045 0.608 -0.041 0.640 -0.137 0.119
ITGV, L -0.024 0.787 0.065 0.465 0.064 0.469
RV, L 0.053 0.549 0.145 0.100 -0.049 0.580
RV/TLC, % 0.175 0.047 0.321 <0.001 0.301 <0.001
PaCO2, mmHg 0.022 0.800 0.021 0.814 0.174 0.048
PaO2, mmHg -0.040 0.650 -0.069 0.432 -0.073 0.408
6MWT, m -0.193 0.028 -0.245 0.005 -0.285 0.001
Borg Score 0.138 0.117 0.202 0.021 0.117 0.185

Ains: area of the inspiratory loop; Aexp: area of the expiratory loop; ΔPalv: difference between end-expiratory and end-inspiratory alveolar pressure; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; IC: inspiratory capacity; VC: slow vital capacity; TLC: total lung capacity; ITGV: intrathoracic gas volume; RV: residual volume; VA: alveolar volume by He dilution method; DLCO: diffusion capacity for carbon monoxide; KCO: transfer coefficient for carbon monoxide; 6MWT: 6 min walking test. Bold numbers indicate significant correlations.