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. 2018 May 8;38(3):BSR20171383. doi: 10.1042/BSR20171383

Figure 1. miR-202 is down-regulated in CML cell lines and suppresses CML cell proliferation.

Figure 1

(A) The expressions of miR-202 seven CML cell lines and isolated leukocytes from a pool of seven healthy blood samples were measured using qRT-PCR. U6 snRNA was used as a loading control. (B) Control mimic or miR-202 mimic was transfected into K562 and KU812 cells for 48 h, followed by the measurements of miR-202 by qRT-PCR. U6 snRNA was used as a loading control. (C) Control mimic or miR-202 mimic was transfected into K562 and (D) KU812 cells for 48 h, followed by the measurements of cell proliferation at 0, 12, 24, 48 and 72 h by MTT assay and (E,F) BrdU assay. The results are presented as mean ± S.D. of triplicates from each of three independent experiments. *P <0.05; **P <0.01; ***P <0.001.