Table 2. Univariate and multivariate logistic regression analysis for poor outcome.
| Parameter | Univariate analysis | Multivariate analysis1 | ||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Age (increase per unit) | 1.15 (1.06–1.27) | <0.001 | 1.10 (1.04–1.18) | 0.003 |
| Male sex | 1.28 (1.03–1.58) | 0.26 | — | |
| BMI (increase per unit) | 1.18 (1.05–1.30) | 0.002 | 1.12 (1.04–1.25) | 0.02 |
| Infarct volume (increase per unit) | 1.20 (1.08–1.33) | 0.001 | 1.16 (1.04–1.27) | 0.01 |
| NIHSS score (increase per unit) | 1.45 (1.21–1.66) | <0.001 | 1.37 (1.18–1.53) | 0.002 |
| Time from onset to blood collection (increase per unit) | 0.97(0.90–1.05) | 0.13 | — | |
| Stroke syndrome | ||||
| TACS | 1.66 (0.65–3.22) | 0.22 | — | |
| PACS | 1.15 (0.81–1.83) | 0.75 | — | |
| LACS | 0.81 (0.47–1.66) | 0.51 | — | |
| POCS | 0.59 (0.32–1.40) | 0.39 | — | |
| Stroke etiology | ||||
| Small-vessel occlusive | 0.64 (0.38–1.33) | 0.45 | — | |
| Large-vessel occlusive | 0.94 (0.68–1.27) | 0.33 | — | |
| Cardioembolic | 1.15 (0.94–1.46) | 0.09 | — | |
| Other | 1.22 (0.98–1.77) | 0.26 | — | |
| Pre-stroke treatment (Yes compared with No) | 0.93 (0.88–0.99) | 0.03 | 0.95 (0.87–1.05) | 0.09 |
| Acute-stroke treatment (Yes compared with No) | 0.85 (0.79–0.92) | 0.006 | 0.91 (0.85–0.95) | 0.01 |
| Moderate-heavy physical activity | 1.87 (1.13–2.56) | 0.02 | 1.64 (1.05–2.68) | 0.06 |
| Blood pressure (increase per unit) | 0.96 (0.90–1.13 | 0.12 | — | |
| Vascular risk factors (Yes compared with No) | 1.44 (1.02–2.01) | 0.04 | 1.36 (0.88–2.15) | 0.18 |
| Hs-CRP (increase per unit) | 1.14 (1.03–1.22) | 0.008 | 1.11 (1.04–1.20) | 0.01 |
| FBG (increase per unit) | 1.06 (1.02–1.14) | 0.005 | 1.03 (1.01–1.07) | 0.008 |
| HDL (increase per unit) | 0.66 (0.50–1.05) | 0.10 | ||
| Triglycerides (increase per unit) | 1.18 (0.92–1.77) | 0.15 | ||
| HOMA-IR | 3.43 (2.21–5.33) | <0.001 | 2.45 (1.59–4.07) | <0.001 |
Abbreviations: HDL, high-density lipoprotein; LACS, lacunar syndrome; PACS, partial anterior circulation syndrome; POCS, posterior circulation syndrome; TACS, total anterior circulation syndrome.
1
Includes the significant risk factors in univariate logistic regression analysis for multivariate logistic analysis (age, BMI, infarct volume, NIHSS score, pre-stroke and acute treatment, physical activity, vascular risk factors and serum levels of Hs-CRP and FBG).