Table 2.
Enriched terms in proteins uniquely segregating with caveolae in gentamicin challenged cells. The 948 proteins uniquely segregating with caveolae in GTM treated cells where selected as the target group for the GOrilla enrichment analysis. The control dataset plus the GTM dataset were chosen as background group. GO terms with a FDR q-value p < 0.05 were considered in the table. “Molecular function” was the only in the GO category reaching significance. The majority of the proteins associated with the enriched terms are involved in protein kinases activity
| Molecular function | |||
|---|---|---|---|
| GO term | Description | FDR q-value | Enrichment (N, B, n, b) |
| GO:0016772 | transferase activity, transferring phosphorous-containing groups | 6.34E-3 | 1.57 (2597.121, 932, 68) |
| GO:0016740 | transferase activity | 1.70E-2 | 1.32 (2597, 289, 932,137) |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 4.09E-2 | 1.60 (2597, 82, 932, 47) |