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. 2018 Apr 19;5(2):e22. doi: 10.2196/mental.8363

Table 7.

Depression (Patient Health Questionnaire 9-item; PHQ-9) simulate (approximated) replacement scores from various adjusted models. GAD-7: Generalized Anxiety Disorder Scale 7-item; GEE: generalized estimating equation; MAR: missing at random; N/A: not applicable.

Source of PHQ-9 estimates Mean score
(95% CI)
Relative percentage accuracy from recontacted cases
(95% CI)
Conclusion drawn about accuracya
Observed symptom score from recontacted cases 8.11 (6.53-10.07) N/A N/A
MAR PHQ-9 baseline and treatment adherence (GEE) 7.47 (6.84-8.15) −8 (−16 to 0) Statistical equivalence
MAR PHQ-9 baseline and treatment adherence (mixed) 7.5 (6.89-8.16) −8 (−19 to 6)  
MAR GAD-7 baseline and treatment adherence (GEE) 7.15 (6.7-7.63) −12 (−24 to 3) Statistical equivalence
MAR GAD-7 baseline and treatment adherence (mixed) 7.28 (6.81-7.78) −10 (−23 to 4)  
MAR treatment adherence (GEE) 6.91 (6.6-7.25) −15 (−19 to −11) Statistical equivalence
MAR treatment adherence (mixed) 7.06 (6.71-7.43) −13 (−26 to 3)  
MAR PHQ-9 baseline (GEE) 6.57 (6.07-7.12) −19 (−25 to −12) Statistical equivalence
MAR PHQ-9 baseline (mixed) 6.54 (6.05-7.07) −19 (−30 to −7)  
MAR comorbidity and education, and age (GEE) 6.31 (5.99-6.65) −22 (−26 to −18) Significant underestimation
MAR comorbidity and education, and age (mixed) 6.33 (6.01-6.66) −22 (−34 to −8)  
MAR comorbidity (GEE) 6.23 (5.9-6.57) −23 (−27 to −19) Significant underestimation
MAR comorbidity (mixed) 6.24 (5.93-6.58) −23 (−35 to −9)  
MAR GAD-7 baseline (GEE) 6.09 (5.82-6.37) −25 (−28 to −21) Significant underestimation
MAR GAD-7 baseline (mixed) 6.12 (5.85-6.4) −25 (−36 to −10)  
MAR age (GEE) 6.03 (5.97-6.08) −26 (−26 to −25) Significant underestimation
MAR age (mixed) 6.07 (6.01-6.13) −25 (−39 to −8)  
MAR Marital Status (GEE) 6 (5.83-6.17) −26 (−28 to −24) Significant underestimation
MAR marital Status (mixed) 6.03 (5.87-6.2) −26 (−38 to −10)  
MAR education (GEE) 5.96 (5.88-6.04) −27 (−28 to −26) Significant underestimation
MAR education (mixed) 5.99 (5.91-6.07) −26 (−40 to −9)  
MAR gender (GEE) 5.94 (5.89-6) −27 (−27 to −26) Significant underestimation
MAR gender (mixed) 5.98 (5.93-6.03) −26 (−40 to −9)  

aRelative accuracy from observed recontacted cases following a clinical follow-up.