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. 2018 May 3;9(5):519. doi: 10.1038/s41419-018-0536-7

Fig. 2. BRD7 inhibits cell proliferation and induces cell apoptosis in breast cancer cells.

Fig. 2

a Western blot analysis of the expression of BRD7 in MCF-7 (left) and MDA-MB-231 (right) cells transfected with pIRES2-EGFP-3Flag/BRD7. b MTT assay in MCF-7 and MDA-MB-231 cells transfected with pIRES2-EGFP-3Flag/BRD7 or pIRES2-EGFP. c Colony formation assay was used to determine the colony forming ability in MCF-7 and MDA-MB-231 cells transfected with pIRES2-EGFP-3Flag/BRD7 or pIRES2-EGFP and quantification. d Cell cycle analysis in MCF-7 and MDA-MB-231 cells transfected with pIRES2-EGFP-3Flag/BRD7 or pIRES2-EGFP and quantification. e Flow cytometric analysis for cell apoptosis in MCF-7 and MDA-MB-231 cells transfected with pIRES2-EGFP-3Flag/BRD7 or pIRES2-EGFP and quantification. Data are expressed as the mean ± S.D. **P < 0.01, ***P < 0.001 vs vector