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. 2018 May 3;9(5):520. doi: 10.1038/s41419-018-0563-4

Fig. 1. Tctn3 KO resulted in abnormal development and prenatal death in mice.

Fig. 1

Mouse embryos at E10.5 were collected and total RNA was extracted. The relative mRNA expression of Tctn1, Tctn2, and Tctn3 in Tctn3 Het KO mice and Tctn3 KO mice was detected by quantitative PCR. N = 3 (a). Mouse embryos at E14.5 were collected, and pictures were taken to examine the head and eyes (b). Polysyndactyly phenomenon at E14.5 days was shown (c). At postnatal stage P0, mice were collected. Alizarin red S and alcian blue staining was performed. Polysyndactyly was shown in Tctn3 KO mice (d)