Fig. 1.

The UGT2B17 gene deletion is associated with its protein abundance (A), rates of testosterone- and DHT-glucuronide formation (B and C, respectively). UGT2B17 diplotypes (haplotype pairs on homologous chromosomes) are associated with UGT2B17 mRNA expression (D), protein abundance (E), testosterone-glucuronide formation (F), and DHT-glucuronide formation (G). Confounding factor, that is, samples from subjects aged younger than 12 years, were excluded from the subanalysis. *P < 0.05; **P < 0.01; ***P < 0.0001. Sample number in each group is shown in parentheses in the x-axis.