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. 2018 Apr 19;115(18):4619–4624. doi: 10.1073/pnas.1719663115

Table 2.

Activity of recombinant CYP9K1 against model substrates and insecticides

Substrate Specific activity/depletion of parental compound, %
−NADPH +NADPH
7-Ethocycoumarin No activity 10.6 ± 1.1
Deltamethrin No depletion 32.0 ± 3.24
Bendiocarb No depletion No depletion
Pyriproxyfen No depletion 38.0 ± 1.3

Activities are given in picomoles of 7-hydroxycoumarin per minute per picomole of P450 for the substrate 7-ethocycoumarin and as percentage depletion of the parental insecticides under assay conditions.