Table 3.
Tumor PTGS2 expression | Quartile of marine ω-3 PUFAs | Ptrenda | |||
---|---|---|---|---|---|
| |||||
1 | 2 | 3 | 4 | ||
Absent/low | |||||
Events/no. at risk | 44/97 | 32/84 | 29/84 | 29/82 | |
HR (95% CI)b | 1.00 | 0.86 (0.53–1.38) | 0.83 (0.52–1.35) | 0.78 (0.48–1.27) | 0.35 |
High | |||||
Events/no. at risk | 13/38 | 24/56 | 11/35 | 5/34 | |
HR (95% CI)b | 1.00 | 1.07 (0.52–2.22) | 0.67 (0.27–1.65) | 0.32 (0.11–0.95) | 0.01 |
Ptrend calculated by modeling the median of each category as a continuous term.
Cox proportional hazards regression model adjusted for age, sex, and energy intake, T-stage, number of positive lymph nodes, baseline performance status, treatment arm, body mass index, physical activity, smoking, and aspirin use.