Table 2.
Effect of SB on the concentration of serum inflammatory markers in control and experimental rats.
| Group | IL-1β (pg/mL) | IL-6 (pg/mL) | IL-10 (pg/mL) | IL-17 (ng/mL) | TNF-α (ng/mL) |
|---|---|---|---|---|---|
| Control | 51.54±5.76 | 22.45±8.67 | 131.56±16.63 | 49.87±6.64 | 88.28±12.45 |
| CIA | 167.34±21.35a** | 108.57±15.66a** | 51.74±7.54a** | 112.58±15.02a** | 177.35±19.62a** |
| SB 20+CIA | 81.45±10.97b** | 66.68±11.77b** | 101.67±11.78b** | 63.74±4.67b** | 120.46±10.24b** |
| SB 40+CIA | 66.87±8.24b** | 41.56±10.75b** | 122.59±10.72b** | 56.80±7.83b** | 100.13±8.94b** |
Data are means ± SD of 12 rats per group.
**
p<0.01
*
p<0.05.
a
CIA vs. control group;
b
SB treatment (20 and 40 mg/kg) vs. CIA group.