Table 1.
Group 1 Placebo (n = 24, M14/F10) | Group 2 Policosanol 10 mg (n = 29, M21/F8) | Group 3 Policosanol 20 mg (n = 31, M22/F9) | |||||
---|---|---|---|---|---|---|---|
Age | 32 ± 14 | 34 ± 16 | 31 ± 12 | ||||
Body composition | Week 0 | Week 24 | Week 0 | Week 24 | Week 0 | Week 24 | |
BMI | 22.3 ± 1.5 | 22.5 ± 1.4 | 23.2 ± 1.8 | 23.4 ± 1.8 | 23.7 ± 1.5 | 23.8 ± 1.3 | |
Subcutaneous fat (kg) | 12.3 ± 2.3 | 12.4 ± 2.1 | 13.6 ± 2.5 | 14.1 ± 2.7 | 13.8 ± 2.5 | 14.4 ± 1.8 | |
Visceral fat (kg) | 1.7 ± 0.5 | 1.6 ± 0.4 | 2.0 ± 0.5 | 2.1 ± 0.6 | 2.0 ± 0.5 | 2.1 ± 0.4 | |
Peripheral BP (mmHg) | Week 0 | Week 24 | Week 0 | Week 24 | Week 0 | Week 24 | |
SphygmoCor | Systolic | 135 ± 12 | 132 ± 11 | 139 ± 16 | 130 ± 15** | 136 ± 8 | 123 ± 11*** |
Diastolic | 88 ± 8 | 84 ± 8 | 89 ± 10 | 87 ± 11 | 87 ± 7 | 81 ± 9* | |
Omron | Systolic | 134 ± 12 | 135 ± 10 | 140 ± 18 | 134 ± 20* | 138 ± 11 | 122 ± 10*** |
Diastolic | 84 ± 9 | 83 ± 9 | 85 ± 12 | 84 ± 15 | 82 ± 10 | 72 ± 10** | |
Mercury | Systolic | 131 ± 6 | 129 ± 8 | 134 ± 12 | 130 ± 17* | 135 ± 6 | 121 ± 9*** |
Diastolic | 83 ± 5 | 81 ± 8 | 84 ± 10 | 82 ± 10 | 84 ± 5 | 75 ± 9* | |
Average | Systolic | 138 ± 9 | 132 ± 6 | 135 ± 13 | 128 ± 6** | 138 ± 12 | 126 ± 13*** |
Diastolic | 87 ± 6 | 83 ± 6 | 86 ± 10 | 83 ± 12 | 87 ± 7 | 79 ± 8** | |
Aortic BP (mmHg) | Week 0 | Week 24 | Week 0 | Week 24 | Week 0 | Week 24 | |
Aortic | Systolic | 123 ± 12 | 117 ± 9 | 130 ± 14 | 120 ± 13* | 123 ± 13 | 113 ± 12*** |
Diastolic | 90 ± 8 | 85 ± 7 | 92 ± 10 | 86 ± 8* | 91 ± 7 | 84 ± 5** | |
Mean arterial pressure | 104 ± 9 | 100 ± 8 | 104 ± 11 | 97 ± 11* | 103 ± 7 | 93 ± 9** | |
Pulse pressure | 32 ± 8 | 32 ± 4 | 35 ± 10 | 30 ± 5 | 32 ± 5 | 29 ± 5 |
Data are expressed as mean±SD.
p < 0.001 vs. week 0;
p < 0.01 vs. week 0;
p < 0.05 vs. week 0 in each group. AU, arbitrary unit; BP, blood pressure; BMI, body mass index.