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. 2018 Mar 21;45(2):86–91. doi: 10.1159/000488060

Table 2.

Extended half-life FIX products. Mean half-lives are given for patients > 12 years onlya

Generic name Name Technology Cell line Molecule length Mean half-life, h
Eftrenanocog alfa Alprolix® Fc-fusion HEK full-length 82
Albutrepenonacog alfa Idelvion® albumin-fusion CHO full-length 102
Nonacog beta pegol Refixia® site-specific PEGylation to activation peptide CHO full-length 93

HEK = Human embryonic kidney; CHO = Chinese hamster ovary.

a

Note that methods to evaluate half-lives differed among studies.