TABLE 1.
Cases Included in the Study, Clinical Data and Localization of the Lesions, Type of Surgical Resection and Regions of Tumor Involvement on Pathological Examination
| Case for Table | Age at Time of Surgery (Years) | Gender | Main Location of Lesion on MRI | MRI Diagnosis | Tissues Resected as Samples for Histology | Anatomical Regions of Samples with Tumor | Pathology Diagnosis |
|---|---|---|---|---|---|---|---|
| 1 | 39 | F | L Amyg | COMPLEX DNT | AMYG, Le, TL, HB, PHG, PES, CUSA | Amyg, small focus In TL | COMPLEX DNT |
| 2a | 26 | F | R parietal | SIMPLE DNT | Fragments of Le | All tissue samples | COMPLEX DNT |
| 3 | 22 | F | L superior frontal gyrus | COMPLEX DNT | Fragments of Le | All tissue samples | COMPLEX DNT |
| 4 | 20 | F | R Amyg, HB | COMPLEX DNT | TL, Le, HB, PES, CUSA | ITG, Le, PES | COMPLEX DNT |
| 5 | 35 | M | R PHG, FG, ITG | COMPLEX DNT | COMPLEX DNT | ||
| 6 | 61 | M | L medial temporal lesion | COMPLEX DNT | TL HB, PHG, PES, CUSA | ITG, HB, PES | COMPLEX DNT |
| 7 | 42 | F | R parietal lobe | COMPLEX DNT | Le, CUSA | In samples of Le | COMPLEX DNT |
| 8a | 28 | M | R medial temporal lesion | SIMPLE DNT | TL and Le | COMPLEX DNT | |
| 9 | 43 | F | R MTG | dGNT | Le and CUSA | In samples of Le | dGNT |
| 10 | 17 | F | R FG | dGNT | TL, HB, PES, CUSA (2) | TL only | dGNT |
| 11 | 31 | M | L ITG, FG | dGNT | LE, CUSA | In samples of Le | dGNT |
| 12 | 48 | F | L mesial temporal lesion | dGNT | TL, HB, Le, PHG, CUSA | TL, ITG, HB, Le, PHG | dGNT |
| 13 | 31 | F | R occipital lobe | dGNT | Le | In samples of Le | dGNT |
| 14 | 16 | M | L STG | dGNT | Le and CUSA | In samples of Le | dGNT |
| 15 | 26 | F | R PHG | dGNT | TL, HB | ITG, PHG, HB | bdGNT |
| 16 | 31 | M | L PHG | dGNT | TL, HB, PES, Le, CUSA (2) | TL, HB, Le | bdGNT |
| 17 | 26 | F | L PHG | dGNT | TL, HB, PHG, PES, CUSA | TL (ITG) HB, PHG, CUSA (NOT PES) | bdGNT |
| 18 | 35 | M | R STG | dGNT | TL, HB, PHG, PES, Le, CUSA | TL and Le | bdGNT |
| 19 | 18 | M | L Amyg | dGNT | TL, HB, PHG, PES, Le, CUSA | PHG, FG, Le, Temporal pole, HB, PES | cdGNT |
| 20 | 24 | M | L MTG | dGNT | Le and CUSA | All tissue samples | cdGNT |
| 21 | 40 | M | L PHG | dGNT | TL, HB, PES, Le, CUSA (2) | PHG, HIPPO, TL | cdGNT |
| 22a | 41 | M | R MTG | COMPLEX DNT | Le, TL, HB, PHG, PES, CUSA | Le and CUSA | SIMPLE DNT |
| 23 | 52 | F | L frontal rectus gyrus | SIMPLE DNT | Le | In all samples of Le | SIMPLE DNT |
| 24 | 60 | F | R PHG | SIMPLE DNT | TL, HB, PHG, PES, AMYG, CUSA | PHG | SIMPLE DNT |
| 25a | 31 | M | L supramarginal gyrus | COMPLEX DNT | Fragments of Le | In all samples of Le | SIMPLE DNT |
| 26 | 26 | F | R MTG | SIMPLE DNT | Fragments of Le | In all samples of Le | SIMPLE DNT |
| 27 | 27 | M | L STG | SIMPLE DNT | Fragments of Le | In all samples of Le | SIMPLE DNT |
The confirmed MRI and pathology diagnosis following review are highlighted in 2 columns. dGNT = diffuse glioneuronal tumor, L = left, R = right, Le = samples from main lesion/lesionectomy, TL = anterior temporal lobectomy (including temporal pole, middle temporal gyrus [MTG], inferior temporal gyrus [ITG] and part of fusiform gyrus [FG], and superior temporal gyrus [STG]), HB = hippocampal body, PHG = parahippocampal gyrus, PES = pes hippocampus, Amyg = amygdala, CUSA = cavitron ultrasonic aspiration samples (either from lesion, amygdala or PHG).
Indicates cases where there was a mismatch between the pathology and the MRI diagnosis.
dGNT had a focal ganglioglioma component.
Cases had a diffuse pattern but with some mixed components of conventional DNT.