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. 2016 Sep 20;18(9):1695–1705. doi: 10.1093/pm/pnw219

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© 2016 American Academy of Pain Medicine.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Overall drug liking and take drug again VAS scores. (A) E_max for overall drug liking VAS. (B) E_max for take drug again VAS. *P < 0.0001, relative to manipulated morphine ER. ^†P = 0.0003, relative to manipulated morphine ER. ADER-IMT = abuse-deterrent, extended-release injection-molded tablets; E_max=peak effect; ER = extended-release; HV = high-volume; LV = low-volume; manip = manipulated; VAS = visual analog scale.