Table 1.
Laboratory findings in different causes of neonatal bleeding
| PT | aPTT | PLT | |
|---|---|---|---|
| Acquired bleeding disorders | |||
| 1. Vitamin K deficiency | ↑ | ↑/= | = |
| 2. Liver failure | ↑ | ↑ | ↓ |
| 3. DIC | ↑ | ↑ | ↓ |
| Inherited bleeding disorders | |||
| 1. Hemophilia A and B | = | ↑ | = |
| 2. von Willebrand disease | = | ↑ | =/↓ |
| 3. Factor XI deficiency | = | ↑ | = |
| 4. Factor XIII deficiency | = | = | = |
| 5. α2-antiplasmin deficiency | = | = | = |
| 6. Plasminogen activator inhibitor 1 deficiency | = | = | = |
| 7. Afibrinogenemia | ↑ | ↑ | = |
| 8. Factor II deficiency | ↑ | ↑ | = |
| 9. Factor V deficiency | ↑ | ↑ | = |
| 10. Factor X deficiency | ↑ | ↑ | = |
| 11. Factor VII deficiency | ↑ | = | = |
PT = Prothrombin time; aPTT =activated partial thromboplastin time; PLT = platelets; DIC = disseminated intravascular coagulation.