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. 2018 Apr 25;24:2541–2549. doi: 10.12659/MSM.906876

Figure 4.

Figure 4

Cell-intrinsic defects of MYSM1-deficient HSCs in engraftment. (A, B) Donor chimerism in competitive repopulation assay. 1×103 LSK cells sorted from wild-type or cKO mice (CD45.2+) were transplanted into lethally irradiated recipients (CD45.1+) together with 2×105 competitor BM cells (CD45.1+). (A) Percentages of donor-derived cells (CD45.2+) in peripheral blood (PB) 8 weeks after transplantation. (B) Percentages of donor-derived cells in LSK and LSK subsets cells of BM 8 weeks after transplantation (n=4 per group).