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. 2018 Mar 19;10(3):453–462. doi: 10.1080/19420862.2018.1433974

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© 2018 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — In vivo protection against RSV infection by intranasally administered RSV-specific IgA and IgG. RSV load was determined in bronchoalveolar fluid from wild-type (WT; closed circles) and human FcαRI transgenic (Tg; open squares) BALB/c mice prophylactically treated with recombinant IgA and IgG variants of (A) palivizumab and (B) motavizumab. Graphs show the percentage of RSV infection; the mean RSV load of the PBS-treated group was set to 100% infection. N=5 mice per group. Data represent the mean ± SEM. Kruskal-Wallis test, * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001.