Table 2. SNPs showing at least one significant association with functional parameters under a nominal level (p Model < 0.05).
| Gene | SNP | MAF | Hand Grip* | ADL° | Walking Time° | |||
| β ± se | pModel | OR (95% CI) |
pModel | β ± se | pModel | |||
|
SLC3A2 CD98 |
rs12804553 | T=0.25 | +2.48 ± 1.15 | 0.029R | ||||
| rs4726 | T=0.20 | -1.40 ± 0.68 | 0.034D | |||||
|
SLC7A5 LAT1 |
rs4329925 | C=0.15 | -1.98 ± 0.96 | 0.027D | ||||
| rs731710 | G=0.48 | 0.47 (0.27-0.81) |
0.005A | |||||
|
SLC7A8 LAT2 |
rs999165 | A=0.19 | -3.09 ± 0.95 | 0.0013D | ||||
| rs12588118 | G=0.27 | -6.41 ± 2.06 | 0.002R | |||||
| rs3783436 | C=0.34 | 0.40 (0.20-0.82) |
0.007A | |||||
|
SLC36A1 PAT1 |
rs357618 | G=0.30 | 0.11 (0.01-0.96) |
0.013R | ||||
| rs357629 | G=0.32 | 0.11 (0.01-0.96) |
0.013R | |||||
|
SLC38A2 SNAT2 |
rs1873793 | C=0.48 | 3.06 (1.36-6.85) |
0.007R | ||||
|
SLC38A7 SNAT7 |
rs9806843 | G=0.34 | + 1.70 ± 0.63 | 0.008D | ||||
Abbreviations: MAF, Minor allele frequency; β, beta coefficient, se, standard error; OR, odds ratio; CI, confidence interval. p Model is the p value of the best genetic model, where R is recessive, D is dominant, and A is additive model.
*Age, sex, and height were included as covariates.
°Age and sex were included as covariates.