Table 3. SNPs showing significant associations with longevity under a nominal level (p Model < 0.05).
Gene | SNP | MAF | OR (CI) | pModel |
SLC3A2 CD98 |
rs12794763 | G=0.15 | 0.42 (0.26-0.68) | 0.0002D |
SLC38A2 SNAT2 |
rs1873793 | C=0.48 | 0.70 (0.50-0.98) | 0.035D |
SLC38A3 SNAT3 |
rs1858828 | T=0.38 | 1.33 (1.06-1.68) | 0.014 A |
SLC38A9 SNAT9 |
rs4865615 | C=0.4 | 0.54 (0.33-0.88) | 0.011R |
rs7704138 | C=0.39 | 0.56 (0.34-0.92) | 0.018R | |
rs10056358 | A=0.14 | 0.66 (0.45-0.96) | 0.029 D |
Abbreviations: MAF, Minor allele frequency; OR, odds ratio; CI, confidence interval. p Model is the p value of the best genetic model, where R is recessive, D is dominant, and A is additive model.
The variable sex was considered a covariate.