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. 2018 Mar 12;8(5):1615–1626. doi: 10.1534/g3.118.200181

Figure 1.

Figure 1

A single extra copy of SRS2 sensitizes wt cells to MMS: (A) Haploids but not diploids show sensitivity to MMS when extra copy of SRS2 on a centromeric plasmid is added. Ten-fold serial dilutions were plated on YEPD plates with increasing amounts of MMS. (B,C) Addition of the SRS2-carrying plasmid does not show a significant change in protein levels. (D) Mimicking diploid gene expression in haploids or deleting RDH54, but not NEJ1 (E) abolishes the sensitization effect.