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. 2018 Mar 12;8(5):1615–1626. doi: 10.1534/g3.118.200181

Figure 2.

Figure 2

Analysis of the role of Srs2 on induced DNA repair: (A) The sensitization effect of SRS2 requires the HR machinery. (B) A schematic representation of strain MK166 and its recombination substrates. (C) DNA damage induces recombination levels (gene conversion and direct-repeat recombination) in wt cells. An extra copy of SRS2 reduces the HR levels. (D) The induced HR in diploid cells is not affected by an extra copy of SRS2. (E, F) in the background of Δrdh54 or Δrad59 there is less GC and DRR induction. An extra copy of SRS2 does not further reduce this effect.