Table 2. Area under the curve for ROC analysis at different activity thresholds for the reference test and CareStart biosensor.
Threshold* | Gold Standard G6PD value |
CareStart G6PD value |
All samples | Only females |
---|---|---|---|---|
IU/g Hb | IU/g Hb | AUC (95%CI) | AUC (95%CI) | |
30% | 2.37 | 2.36 | 0.52 (0.49–0.55) | 0.52 (0.48–0.55) |
40% | 3.16 | 3.14 | 0.64 (0.58–0.70) | 0.68 (0.60–0.77) |
70% | 5.54 | 5.50 | 0.85 (0.79–0.90) | 0.79 (0.71–0.86) |
80% | 6.33 | 6.28 | 0.91 (0.86–0.96) | 0.86 (0.78–0.94) |
*Assuming equivalency in G6PD activity thresholds in terms of % of normal activity