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. 2018 May 7;215(5):1417–1435. doi: 10.1084/jem.20171784

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© 2018 Durai et al.

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Figure 10. — Deletion of Flt3 rescues the severe DC defect in Flt3l^−/− mice. (A–E) Splenocytes from mice of the indicated genotypes at 8-wk of age were analyzed by flow cytometry for DC populations. (A) Shown are representative two-color histograms of live cells. Numbers specify the percentage of cells within the indicated gates. (B–E) Summary data for the percentage (B) and number (C) of splenic cDCs and the percentage (D) and number (E) of splenic pDCs in mice of the indicated genotypes. Dots represent biological replicates; small horizontal lines indicate the mean. Data are pooled from six independent experiments (n = 4–5 mice per genotype). *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001 using unpaired, two-tailed Student's t test.