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. 2018 Apr 20;9(30):21296–21312. doi: 10.18632/oncotarget.25090

Figure 2. EcTI did not interfere in apoptosis.

Figure 2

Effect of EcTI on cell death (A) in GBM U87 cells, MSCs, and coculture after 24 h of treatment using 50 μM and 100 μM EcTI final concentrations. The cell death was performed as described in Material and Methods. Effect of EcTI analysis on the tumor protein p53, Tp53 (B); p21, Cdkn1A (C); and Bax/Bcl2 ratio (D). mRNA levels in U87 cells treated with EcTI (2.5, 5, 10, 20, and 100 μM) for 72 h and presented relative to control non-treated U87 cells. The error bars represent SD (*p < 0.05, **p< 0.005, ***p< 0.0005).