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The gene expression ratio of late to early generation tumors of seven angiogenesis-related genes (A) and five cancer stem cell-related genes (B). The genes were significantly up-regulated in late generation tumors of the ED-15, HL-16, and LA-19 models, but not in late generation tumors of the BK-12 model. Columns: mean of three late generation tumors divided by mean of three early generation tumors.
