Table 1. Genes showing significantly higher expression in late than in early generation tumors of the ED-15, HL-16, and LA-19 cervix cancer models.

Angiogenesis-related genes

CTGF (Connective tissue growth factor)

CXCL1 (Chemokine (C-X-C motif) ligand 1)

EDN1 (Endothelin 1)

IL1B (Interleukin 1 beta)

IL6 (Interleukin 6)

IL8 (Interleukin 8)

TNF (Tumor necrosis factor)

Stem cell-related genes

KLF4 (Kruppel like factor 4)

MYC (MYC proto-oncogene, bHLH transcription factor)

PLAUR (Plasminogen activator, urokinase receptor)

SNAI1 (Snail family transcriptional repressor 1)

IL8 (Interleukin 8)