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. Author manuscript; available in PMC: 2019 May 15.
Published in final edited form as: J Immunol. 2018 Apr 6;200(10):3407–3419. doi: 10.4049/jimmunol.1701416

Figure 6. E-FABP deficiency reduces CD11c+ macrophages in obese mice.

Figure 6

WT and E-FABP−/− mice were fed on HFD (60% fat) for 20 weeks. Different tissues or organs were collected, respectively from the obese WT and E-FABP−/− mice (n=5) for analysis of the presence of CD11b+CD11c+ macrophages. (A-D) Flow cytometric surface staining for analysis of CD11b+CD11c+ macrophages in bone marrow (A), liver (B), lung (C) and skin (D). Average percentage of CD11c+ cells is shown in the right panel. (E-G) Measurement of cytokine levels of IL-6 (E), IL-1β (F) and TNFα (G) in the serum collected from obese WT and E-FABP−/− mice by ELISA. Data shown as mean ± SEM (*p<0.05, **p<0.01), and are representative of at least two independent experiments. Also see Figure S2.