Table 3.

Association between CBC and risk of biochemical recurrence after RP among black and white men

	All HR (99% CI)	p-value	Black men HR (99% CI)	p-value	White men HR (99% CI)	p-value	Race X CBC p-interaction
Unadjusted
Neutrophils	0.99 (0.93–1.06)	0.81	1.05 (0.95–1.16)	0.18	1.00 (0.90–1.11)	0.99	0.36
Lymphocytes	1.05 (0.89–1.23)	0.43	1.06 (0.85–1.33)	0.50	0.99 (0.78–1.25)	0.88	0.58
Platelets	1.01 (0.99–1.03)	0.088	1.02 (0.99–1.05)	0.079	1.01 (0.98–1.03)	0.44	0.46
NLR	1.01 (0.92–1.11)	0.76	1.09 (0.95–1.26)	0.096	1.03 (0.91–1.17)	0.55	0.44
PLR	1.00 (1.00–1.00)	0.44	1.00 (1.00–1.00)	0.34	1.00 (1.00–1.00)	0.50	0.87
Adjusted*
Neutrophils	1.03 (0.96–1.10)	0.34	1.02 (0.92–1.13)	0.64	1.04 (0.94–1.15)	0.30	0.83
Lymphocytes	1.00 (0.84–1.18)	0.94	0.97 (0.77–1.22)	0.73	1.01 (0.78–1.29)	0.95	0.67
Platelets	1.02 (1.00–1.04)	0.025	1.02 (0.99–1.05)	0.044	1.01 (0.98–1.04)	0.33	0.25
NLR	1.06 (0.97–1.17)	0.10	1.07 (0.93–1.23)	0.23	1.07 (0.94–1.21)	0.18	0.95
PLR	1.00 (1.00–1.00)	0.049	1.00 (1.00–1.01)	0.040	1.00 (1.00–1.00)	0.35	0.28

^*Adjusted for VA center and clinical and pathological characteristics: age, PSA, year of surgery, pathological Gleason score, positive margins, extracapsular extension, seminal vesicles and lymph node involvement

NLR= neutrophil-lymphocyte ratio; PLR= platelet-lymphocyte ratio; HR=hazard ratio