Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 8;8:7182. doi: 10.1038/s41598-018-25208-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Confocal images of fluorophores expressed in four cell types in the cortex (approximately layer III-IV) of different mouse lines. (a) Green fluorescent protein (GFP) is expressed in microglia of Cx3cr1-gfp mouse. (b) Merged image of Cyan fluorescent protein (CFP) expressed in oligodendrocytes, yellow fluorescent protein (YFP) expressed in neurons and Discosoma sp. red fluorescent protein (DsRed) expressed in astrocytes of Prism mouse. (c) Merged image of CFP expressed in oligodendrocytes, GFP expressed in microglia, YFP expressed in neurons and DsRed expressed in astrocytes of quadruple-colored ‘PrismPlus’ mouse line. Single channel images from Prism and PrismPlus mouse lines are shown right to the merged images, b & c, respectively. Z-stack images of 20 microns thick sections were acquired either sequentially (a) or in lambda mode (b,c) using Zeiss LSM 710, 20x/0.8 NA objective and are presented as maximum projected intensity. Scale bar = 50 µm.