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. 2018 May 8;8:7119. doi: 10.1038/s41598-018-25669-1

Table 3.

Detailed distribution of copy number variations detected in 66 intrahepatic cholangiocarcinomas. Related to Fig. 2.

Gene Poor Good Total p-value*
33 [%] 33 [%] 66 [%]
APC 2 [6.1] 1 [3.0] 3 [4.5]
ARID1A 3 [9.1] 5 [15.2] 8 [12.1]
CDKN2A 12 [36.4] 12 [36.4] 24 [36.4]
CCND1 9 [27.3] 8 [24.2] 17 [25.8]
EGFR 1 [3.0] 1 [3.0] 2 [3.0]
EPHA7 4 [12.1] 6 [18.2] 10 [15.2]
ERBB2 4 [12.1] 5 [15.2] 9 [13.6]
FGFR3 9 [27.3] 5 [15.2] 14 [21.2]
FHIT 8 [24.2] 11 [33.3] 19 [28.8]
KRAS 8 [24.2] 9 [27.3] 17 [25.8]
MET 11 [33.3] 5 [15.2] 16 [24.2] 0.15
MYC 10 [30.0] 5 [15.2] 15 [22.7] 0.24
PTEN 5 [15.2] 5 [15.2] 10 [15.2]
RB1 2 [6.1] 2 [3.0]
ROS 1 [3.0] 3 [9.1] 4 [6.1]
SMAD4 4 [12.1] 4 [12.1] 8 [12.1]
SRC 8 [24.2] 10 [30.3] 18 [27.3]
TP53 7 [21.2] 7 [10.6] 0.024

*Fisher test for multiple comparison was used as appropriated.