Table 1.
Clinical characteristics of early-stage NSCLC patients, healthy controls (HC) and patients with benign lung disease (LBD) enrolled in this study.
| Characteristic | Non-targeted metabolomics | Targeted metabolomics | ||
|---|---|---|---|---|
| NSCLC patients | HC | NSCLC patients | HC | |
| Sample size | 90 | 90 | 30 | 30 |
| Age range (years) | 58.1 ± 9.0 | 53.0 ± 11.8 | 62.1 ± 6.7 | 51.7 ± 7.1 |
| Sex | ||||
| Male | 40 | 42 | 21 | 19 |
| Female | 50 | 48 | 9 | 11 |
| Pathological type | ||||
| ADCa | 50 | — | 15 | — |
| SqCCb | 30 | — | 15 | — |
| TNM stagec | ||||
| Stage I | 81 | — | 15 | — |
| Stage II | 9 | — | 15 | — |
aADC: Adenocarcinoma.
bSqCC: Squamous cell carcinoma.
cUnion for International Cancer Control (UICC) TNM Classification of lung cancer (8th ed., 2017).